翻訳と辞書 |
Mir-624 microRNA precursor family : ウィキペディア英語版 | Mir-624 microRNA precursor family
mir-624 microRNA is a short non-coding RNA molecule belonging both to the family of microRNAs and to that of small interfering RNAs (siRNAs). MicroRNAs function to regulate the expression levels of other genes by several mechanisms, whilst siRNAs are involved primarily with the RNA interference (RNAi) pathway. siRNAs have been linked through some members to the regulation of cancer cell growth, specifically in prostate adenocarcinoma. ==Upregulation in the WI-38 cell line== miR-624 has been found to be upregulated in the WI-38 cell line of human fibroblasts in growth arrest states; there was a 1.9 fold increase observed in both cell quiescence and senescence, and a further increased 2.1 fold increase with H202-premature senescence.〔 〕 It has additionally been found to target the (CASP3) gene responsible for encoding the protein caspase 3.
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Mir-624 microRNA precursor family」の詳細全文を読む
スポンサード リンク
翻訳と辞書 : 翻訳のためのインターネットリソース |
Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.
|
|